Bohareng ba katleho ea sejoale-joale ea biopharmaceutical - ho tloha ho liente tse pholosang bophelo ho ea ho li-anti-monoclonal antibodies (mAbs) le liprotheine tse kopanyang hape - ho na le sesebelisoa sa bohlokoa: Bioreactor (Fermenter). Hase feela sekepe, empa ke tikoloho e laoloang ka hloko moo lisele tse phelang li etsang mosebetsi o rarahaneng oa ho hlahisa limolek'hule tsa phekolo. IVEN e eme ka pele, e sa fane ka li-bioreactors feela, empa litharollo tse kopantsoeng tsa boenjiniere tse matlafatsang indasteri ena ea bohlokoa.
Precision E Engineered for Life: Lintlha tsa Bohlokoa tsa IVEN Bioreactors
VEN li-bioreactorsli etselitsoe ho fihlela litlhoko tse nepahetseng tsa tlhahiso ea biopharmaceutical:
Taolo ea Ts'ebetso e sa Lekanyetsoang: Mekhoa e tsoetseng pele e laola litekanyetso tsa bohlokoa - mocheso, pH, oksijene e qhibilihisitsoeng (DO), ho ferekana, ho fepa limatlafatsi - ka mokhoa o nepahetseng le botsitso bo ikhethang, ho netefatsa kholo e nepahetseng ea lisele le boleng bo tsitsitseng ba sehlahisoa.
Scalability & Flexibility: Keketseho e se nang moeli ho tloha ho li-benchtop tsa laboratori bakeng sa R&D le nts'etsopele ea ts'ebetso, ka li-bioreactors tse lekantsoeng, ho isa lits'ebetsong tse kholo tsa tlhahiso, kaofela ha ts'ebetso e ntse e boloka botsitso.
Kholiseho ea Bohlokoa: E entsoe ka moralo oa bohloeki (bokhoni ba CIP / SIP), lisebelisoa tsa boleng bo holimo (316L tšepe e sa hloekang kapa li-polymers tse sebetsang hantle), le litiiso tse matla ho thibela tšilafalo - ea bohlokoa haholo bakeng sa tlhahiso ea GMP.
Motsoako o Phahameng ka ho Fetisisa le Phetisetso ea Boima: Meetso e ntlafalitsoeng ea li-impeller le sparger e netefatsa ho tsoakana ho homogeneous le phetisetso e nepahetseng ea oksijene, e leng bohlokoa bakeng sa litloaelo tse phahameng tsa lisele tsa mammalian.
Tlhokomelo e Tsoetseng Pele le Boiketsetso: Li-sensor tse kopantsoeng le litsamaiso tse tsoetseng pele tsa taolo (SCADA/MES e lumellana) li fana ka lintlha tsa nako ea nnete mme li nolofalletsa taolo ea ts'ebetso e ikemetseng bakeng sa ts'epo e ntlafalitsoeng le ts'epo ea data.
Driving Innovation in Pharmaceutical Production
Li-bioreactor tsa VEN ke lisebelisoa tsa bohlokoa ho pholletsa le biopharma spectrum:
Tlhahiso ea Vaccine: Ho hlaolela lisele tse anyesang (mohlala, Vero, MDCK) kapa lisele tse ling ho hlahisa likokoana-hloko kapa li-antigen bakeng sa liente tsa moloko o latelang.
Li-Antibodies tsa Monoclonal (mAbs): Ho tšehetsa tlhahiso e phahameng ea lihlahisoa tsa li-antibodies tse rarahaneng tse sebelisang li-cell CHO, NS0, kapa SP2/0 tse matla.
Recombinant Protein Therapeutics: Ho etsa hore ho be le polelo e nepahetseng le secretion ea liprotheine tsa bohlokoa joalo ka lihomone, li-enzyme le lintlha tsa kholo.
Cell & Gene Therapy (CGT): Ho thusa ka ho atolosoa ha likokoana-hloko tsa kokoana-hloko (mohlala, AAV, Lentivirus) kapa lisele tsa phekolo ka botsona ka mekhoa e emisitsoeng kapa e khomarelang.
Tsebo ea Mammalian Cell Culture: IVEN e sebetsa ka ho khetheha litlhoko tse rarahaneng tsa mekhoa ea lisele tsa mammalian, e fana ka litharollo tse lokiselitsoeng bakeng sa mela e bonolo ea lisele.
Ka Ntle ho Bioreactor: Molemo oa VEN - Molekane oa Hao oa Bofelo
IVEN e utloisisa hore bioreactor ke karolo e le 'ngoe ka har'a tikoloho e rarahaneng ea tlhahiso. Re fana ka litharollo tse felletseng tsa boenjiniere tse akaretsang bophelo bohle ba projeke:
Boenjiniere ba Setsebi le Moralo: Sehlopha sa rona se theha meralo ea litsi tse ntlafalitsoeng, tse sebetsang hantle le tse lumellanang le meralo ea ts'ebetso e tsamaellanang le molek'hule le sekala sa hau se ikhethileng.
Tlhahiso e nepahetseng: Ho etsoa ha boemo bo holimo ho netefatsa litekanyetso tse phahameng ka ho fetisisa tsa li-bioreactor skids, likepe, li-module tsa liphaephe (pre-fab / PAT), le mekhoa e thusang.
Taolo e Behaneng ea Morero le Kaho: Re laola ho rarahana, ho netefatsa hore projeke ea hau - ho tloha setsing sa liteko ho isa setsing se felletseng sa GMP - se fanoa ka nako le ka tekanyetso.
Ts'ehetso ea netefatso: Thuso e felletseng ka liprothokholo tsa DQ, IQ, OQ, PQ le ts'ebetso, ho netefatsa boitokisetso ba taolo (FDA, EMA, joalo-joalo).
Ts'ebeletso ea Lefatše le Ts'ehetso: Mananeo a ts'ebetso a ts'ebetso, ho rarolla mathata ka potlako, likarolo tse ling, le boiphihlelo ba ts'ebetso ea ts'ebetso ho eketsa ts'ebetso le tlhahiso ea setsi sa hau.
Hore na o qala liphekolo tsa morao-rao ka laboratoring, o phahamisa motho ea tšepisang, kapa o etsa tlhahiso e phahameng ea khoebo, IVEN ke molekane oa hau ea inehetseng. Re fana ka lits'ebetso tse ikhethileng tsa bioreactor le litharollo tse akaretsang tsa boenjiniere - ho tloha mohopolong oa pele ka moralo, kaho, netefatso, le ts'ehetso e tsoelang pele ea ts'ebetso.
Notlolla bokhoni bo felletseng ba li-bioprocesses tsa hau.Ikopanye le VENkajeno ho fumana hore na theknoloji ea rona ea bioreactor le boiphihlelo bo kopaneng ba boenjiniere bo ka potlakisa tsela ea hau ea ho fana ka meriana e fetolang bophelo.
Nako ea poso: Jun-30-2025