Lefats'eng le ntseng le tsoela pele latlhahiso ea biopharmaceutical, tlhokahalo ea katleho, ho tenyetseha le ho tšepahala ha ho mohla e kileng ea e-ba kholoanyane. Ha lik'hamphani tsa meriana li ntse li loanela ho fihlela tlhoko e ntseng e hola ea lefats'e ea biologics joalo ka liente, li-antibodies tsa monoclonal le liprotheine tse nchafatsang, litharollo tse ncha li bohlokoa. Kenya BioProcess Modular System - e leng mokhoa oa ho lokisa mokelikeli o hahelletsoeng ho nolofatsa ts'ebetso ea tlhahiso ha o ntse o netefatsa boleng bo holimo le maemo a polokeho.

BioProcess modular system ke eng?

TheSistimi ea modular ea BioProcesske tharollo ea morao-rao e etselitsoeng indasteri ea biopharmaceutical. Moralo oa eona oa 3D modular o fana ka phetoho e ke keng ea bapisoa, e lumellang lik'hamphani ho hlophisa mela ea tlhahiso ho latela litlhoko tse itseng. Modularity ena ha e thuse feela ho kopanngoa ha likarolo tse sa tšoaneng, empa hape ho bonolo ho atolosa, e leng se loketseng haholo bakeng sa tlhahiso ea bongata le tlhahiso e nyenyane ea batch.

Lintlha tsa Bohlokoa le Melemo

1. 3D Modular Design

Tšobotsi e ikhethang eaSistimi ea modular ea BioProcesske moralo oa eona o mocha oa 3D modular. Mohaho ona o lumella ho kopanngoa ka mokhoa o se nang moeli oa li-module tse fapaneng, e 'ngoe le e' ngoe e sebetsa ka mokhoa o itseng ts'ebetsong ea tlhahiso. Ebang e sebelisetsoa ho kopanya, ho hloekisa kapa ho boloka, mochine o mong le o mong o ka etsoa ho finyella litlhoko tse ikhethang tsa bioproduct e ntseng e etsoa. Ho tenyetseha hona ho bohlokoa 'marakeng o nang le tlhoko e ntseng e hola ea lihlahisoa tse fapaneng tsa baeloji.

2. Automation control system

Automation e bohareng ba litsamaiso tsa modular bakeng sa bioprocessing. Sistimi ena e na le mekhoa e tsoetseng pele ea taolo ho okamela lits'ebetso tsa tlhahiso, ho hloekisa le ho etsa sterilization. Mokhoa ona oa boiketsetso ha o eketse ts'ebetso feela, hape o fokotsa kotsi ea liphoso tsa batho mme o netefatsa hore sehlopha ka seng se fihlela litekanyetso tse tiileng tsa boleng. Bokhoni ba ho iketsetsa lits'ebetso tsena tsa bohlokoa bo lumella lik'hamphani tsa meriana ho tsepamisa maikutlo ho boqapi le nts'etsopele ea lihlahisoa ho fapana le ho ts'oaroa ke ts'ebetso ea matsoho.

3. Tekolo e Feletseng ea Kotsi le Netefatso

Lefapheng la biopharmaceutical, ho latela litekanyetso tsa taolo ho ke ke ha buisanoa. Litsamaiso tsa modular tsa BioProcess li sebelisa moralo o matla oa tlhahlobo ea kotsi o kenyelletsang likarolo tse 'maloa tsa bohlokoa: Tlhahlobo ea Kotsi (RA), Boithuto ba Moqapi (DQ), Tlhophiso ea ho Kenya (IQ) le Operational Qualification (OQ). Mokhoa ona o felletseng o netefatsa hore karolo e 'ngoe le e' ngoe ea sistimi e hlahlojoa le ho netefatsoa ka botlalo, e fa lik'hamphani tsa meriana kholiseho ea hore lits'ebetso tsa bona tsa tlhahiso li bolokehile ebile lia sebetsa.

4. Tlatsa litokomane tsa netefatso

E 'ngoe ea liqholotso tsa bohlokoa ka ho fetisisa tlhahisong ea biopharmaceutical ke ho boloka litokomane tse felletseng tsa taolo ea melao. Sistimi ea modular ea BioProcess e rarolla phephetso ena ka ho fana ka sete e felletseng ea litokomane tsa netefatso. Litokomane tsena li sebetsa e le rekoto e felletseng ea moralo oa sistimi, ho kenya le ho sebetsa, ho nolofatsa lik'hamphani ho bonts'a boikamahanyo nakong ea lihlahlobo le tlhahlobo.

Tšusumetso ho lik'hamphani tsa meriana

Kenyelletso eaSistimi ea modular ea BioProcesske phetoho ea lipapali bakeng sa lik'hamphani tsa meriana. Ka ho ntlafatsa lits'ebetso tsa tlhahiso le ho eketsa li-automation, lik'hamphani li ka fokotsa haholo nako ea ho bapatsa lihlahisoa tse ncha tsa baeloji. Sena ke sa bohlokoa haholo-holo tikolohong ea kajeno e potlakileng, moo bokhoni ba ho arabela ka potlako matšokelong a hlahang a bophelo bo botle a kang mafu a seoa a ka pholosang bophelo.

Ho feta moo, ho feto-fetoha ha maemo ho fanoeng ke moralo oa modular ho lumella lik'hamphani ho ikamahanya le maemo ka potlako ho arabela litlhoko tse fetohang tsa mmaraka. Hore na e eketsa tlhahiso ea ente e ncha kapa e ikamahanya le maemo bakeng sa "anti-monoclonal antibody" e ncha, lisistimi tsa BioProcess modular li fana ka boiphihlelo bo hlokahalang ho lula u le tlholisano.

Ha indasteri ea biopharmaceutical e ntse e hola le ho hola, tlhoko ea litharollo tse ncha tse kang bioprocessing modular system e ntse e bonahala haholo. Ka eonaMoqapi oa modular oa 3D, tsamaiso e ikemetseng ea taolo, tlhahlobo e feletseng ea kotsi le litokomane tse feletseng tsa ho netefatsa, tsamaiso ena e na le monyetla oa ho fetola tsela eo lik'hamphani tsa meriana li hlahisang biologics ka eona.

Lefatšeng leo ho lona ho sebetsa hantle, polokeho le ho latela melao ea molao li tlang pele.Sistimi ea modular ea BioProcesshlahella joalo ka mabone a boqapi. Ka ho amohela mokhoa ona o tsoetseng pele oa ho lokisa mokelikeli, lik'hamphani tsa meriana li ke ke tsa eketsa bokhoni ba tlhahiso feela empa hape li kenya letsoho boitekong ba lefats'e ba ho fana ka biologics e pholosang bophelo ho ba hlokang. Bokamoso ba tlhahiso ea biopharmaceutical bo fihlile, ke modular, othomathike, 'me o ikemiselitse ho tobana le mathata a hosane.